… role in enhancing cells to cisplatin-induced cell death. … of p21 expression in an entirely
p53-independent fashion, as the … of p14 ARF in sensitizing p53 mutated osteosarcoma cells to …

… to cisplatin in a p53-independent manner, suggesting that DMTF1α could sensitize cells
towards cisplatin in an p14 ARF -dependent/p53-independent fashion [19]. Moreover, early …

… will allow cancer cells to evade cisplatin-induced cell death [14… of cell death via p53 signaling,
a p53-independent apoptotic … -methylating agent decitabine sensitized human colon tumor …

… a negative feedback manner to maintain cellular homeostasis … of ARF tumor suppressor (p14
ARF in human and p19 ARF in … Human osteosarcoma U2OS cells were cultured in MacCoy’…

… that expression of p14 ARF and/or p16 INK4a may sensitize cancer cells to imatinib treatment
[… observed in osteosarcoma cell lines in response to cisplatin-induced apoptosis, however, …

… with autophagy through the p14ARF (p19ARF in mouse, and … resensitize H460/cis cells to
cisplatin-induced cell death [84]. … -induced cell death also in a p53-independent manner [115]. …

… p14ARF overexpression can increase sensitivity to cisplatin-induced apoptosis in human
osteosarcoma cells … P16 INK4a also sensitized cells to cisplatin-mediated apoptosis [35]. We …

… Interestingly, the response to dexamethasone, a p53-independent inducer of apoptosis, … ,
thereby sensitizing to platins, has yet to be researched. However, broadly targeting of p14ARF …

… , mitochondrial membrane permeabilization, activation of apoptotic signaling and induction
of cell death [76–78]. Cell metabolism is essential to control oxidants levels. In cancer …

… We discuss that P14 ARF (ARF) functions as a negative … and NOXA) after cisplatin-induced
DNA damage [106]. … and was most likely regulated in a P53-independent manner [39]. It was …